Websialyl-Lewis X: A tetrasaccharide carbohydrate antigen that attaches to O-glycans on cell surfaces. Physiology The sialyl-Lewis X determinant, E-selectin ligand carbohydrate, is constitutively expressed on granulocytes and monocytes, and mediates their extravasation during inflammation; resting Th2 and B cells do not express sialyl-Lewis X, ... WebJun 11, 2004 · Divergent syntheses of sulfated sialyl Lewis X oligosaccharides corresponding to the core 1 and core 6 branches of the l-selectin ligand are reported. These synthetic targets incorporate a selectively protected serine residue at the reducing terminus, providing a functional handle for further conjugation.

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WebIt has been established that sialyl Lewis x in core 2 branched O-glycans serves as an E- and P-selectin ligand. Recently, it was discovered that 6-sulfosialyl Lewis x in extended core 1 O-glycans, NeuNAcα2→3Galβ1→4(Fucα1→3(sulfo→6))GlcNAcβ1→ 3Galβ1→3GalNAcα1→Ser/Thr, functions as an L-selectin ligand in high endothelial … sims 4 scaramouche hair

Alexa Fluor® 647 anti-human Sialyl Lewis X (dimeric) Antibody

Sialyl Lewis (sLeX), also known as cluster of differentiation 15s (CD15s) or stage-specific embryonic antigen 1 (SSEA-1), is a tetrasaccharide carbohydrate which is usually attached to O-glycans on the surface of cells. It is known to play a vital role in cell-to-cell recognition processes. It is also the means by which … See more Sialyl-Lewis X is a tetrasaccharide composed of a sialic acid, fucose and an N-acetyllactosamine. Its systematic name is 5-acetylneuraminyl-(2-3)-galactosyl-(1-4)-(fucopyranosyl-(1-3))-N-acetylglucosamine (Neu5Acα2-3Galβ1 … See more Leukocyte homing Sialyl-Lewis is important in leukocyte tethering and rolling. Leukocytes move through the blood stream and then tether themselves to the … See more The term Lewis in its name comes from the name of a family of people who suffered from a red blood cell incompatibility. The studies done on these individuals' red … See more Leukocyte adhesion deficiency Defective synthesis of the sialyl Lewis antigen results in immunodeficiency (leukocyte adhesion deficiency type 2). Defective synthesis can be caused by the loss of fucosyltransferase, impairing the glycosylation of the … See more • CA19-9 (Sialyl-Lewis A) See more • Chen, G.-Y.; Osada, H.; Santamaria-Babi, L. F.; Kannagi, R. (7 November 2006). "Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes" See more WebResearchGate WebHigh amounts of sialyl Lewis(a) are present in human adenocarcinomas of the colon, pancreas and stomach. A growing amount of data suggests that this carbohydrate … sims 4 scar cc maxis match