Phospho irf1

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August undefined, 2024

WebMar 11, 2024 · IRF1 (Interferon Regulatory Factor-1) is the prototype of the IRF family of DNA binding transcription factors. IRF1 protein expression is regulated by transient up-regulation in response to... WebApr 19, 2024 · Mutation of Tyr613 on IL-27Rα decreased IL-27-induced STAT1 phosphorylation by 80% but had limited effect on STAT3 phosphorgylation. Strong receptor/STAT coupling by IL-27 initiated a unique gene expression program, which required sustained STAT1 phosphorylation and IRF1 expression and was enriched in classical …

GSK3β-SCF-FBXW7 mediated phosphorylation and ubiquitination of IRF1 …

WebAug 1, 2024 · A and B: Western blot image of IRF1, phospho-Akt, total Akt, and β-Actin in IRF1-FLAG overexpressed HEK293T (A) or Calu3 (B) cells treated with insulin (100 nM) at the indicated time points. C: Western blot image of IRF1 and β-Actin in HEK293T treated with TNF-α with the indicated concentrations for 24 h. D: Western blot image of IRF1 ... WebIRF1 Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible … cancer stem cell glycosylation

GSK3β-SCFFBXW7α mediated phosphorylation and ubiquitination of IRF1 …

WebBY-3451R phospho-TOPO II Alpha （Ser1106）磷酸化DNA拓普西异构酶Ⅱ抗体进口/国产 BY-1975R-FITC DAXX 死亡相关蛋白6抗体进口/国产 BY-1404R-FITC IRF-1 干扰素调节因子1抗体进口/国产 WebIHC image of FGFR1 (phospho Y654) staining in Human breast adenocarcinoma formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the … WebIRF1-knockout HeLa cells were generated using the clustered, regularly interspaced palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system, which was performed by ToolGen (Seoul, South Korea). The sequence of single-guide (sg)RNA used to target the human IRF1 gene was CTCGGATGCGCATGAGACCC TGG. fishing unlimited nags head nc

CKII alpha Antibody Affinity Biosciences LTD 亲科生物官网

Anti-FGFR1 (phospho Y654) antibody (ab59194) Abcam

Web人抗酿酒酵母抗体(IgA)ELISA试剂盒；英文名称： Human anti-saccharomyces cerevisiae antibody IgA ELISA Kit ；实验名称：人抗酿酒酵母抗体(IgA)ELISA试剂盒；实验别名：人抗酿酒酵母抗体(IgA)ELISA试剂盒 48T/96T ；规格： 48T/96T 报价人抗酿酒酵母抗体(IgA)ELISA试剂盒实验目的：本试剂盒仅供研究使用，用于用于测定 ... WebJan 21, 2024 · The eponymous member of the interferon regulatory factor (IRF) family, IRF1, was originally identified as a nuclear factor that binds and activates the promoters of type I interferon genes. However, subsequent studies using genetic knockouts or RNAi-mediated depletion of IRF1 provide a much broader view, linking IRF1 to a wide range of ... cancer stem-like cells cscsWebPhospho-IRF-7 (Ser471/472) Antibody detects transfected levels of IRF-7 when phosphorylated at Ser471 and 472. Species Reactivity: Human Source / Purification … fishing uno

"WebApr 16, 2002 · Stimulates both innate and acquired immune responses through the activation of specific target genes and can act as a transcriptional activator and repressor … " - Phospho irf1

Phospho irf1

WebWe hypothesize that our methodology will enable the efficient identification of IRF-specific and pan-IRF inhibitors that can be used for the treatment of IRF-dependent disorders and malignancies. Introduction In 1988 the first interferon regulatory factor (IRF) was identified and named IRF1 ( 1, 2 ). WebNational Center for Biotechnology Information

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WebPhospho-IRS1 (Tyr612) Antibody (44-816G) in IHC (P) Immunohistochemistry analysis of Phospho-IRS1 (pY612) showing staining in the cytoplasm and nucleus of paraffin-embedded human skeletal muscle tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM ... WebMar 11, 2024 · IRF1 is phosphorylated by GSK3β. ( A) Sequence conservation of the putative GSK3β phospho-target sequence in different species. The phosphorylated T180 and the …

WebJun 3, 2024 · The antibodies were as follows: PD-L1 #13684, PD-L2 #82723, STAT1 #9172, JAK1 #3344, phospho-JAK1 #74129, IRF1 #8478, JAK2 #3230, phospho-JAK2 #3771; host rabbit (Cell Signalling Technology Europe, Frankfurt a.M., Germany); β-actin (#MAK6019); host mouse (Linaris, Dossenheim, Germany). Then, secondary antibodies against rabbit … WebMay 1, 2024 · Following immunoprecipitation with anti-FLAG beads, western blots were performed using the anti-pT/S antibody and re-probed with anti-FLAG to determine total IRF1 protein, and a representative blot is shown. The ratio phospho-IRF1 to total IRF1 was quantified by densitometry, and data from three independent experiments are shown.

WebIRF-1 is serine-phosphorylated by casein kinase II (CKII) at two clustered sites, one in the DNA-binding domain (amino acids 138-150) and another in the transactivation domain … WebPhospho-IRF7 (Ser437/438) IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role …

WebAnti-FGFR1 (phospho Y654) antibody See all FGFR1 primary antibodies Description Rabbit polyclonal to FGFR1 (phospho Y654) Host species Rabbit Specificity Binds human and mouse FGFR1 only when phosphorylated at tyrosine 654 and rat FGFR1 only when phosphorylated at tyrosine 561. Tested applications Suitable for: ICC/IF, IHC-P, WB more …

WebBackground: Antiviral innate immunity depends on the combination of parallel pathways triggered by virus detecting proteins in the Toll-like receptor (TLR) family and RNA helicases, such as Rig-I (retinoic acid-inducible gene I) and MDA-5 (melanoma differentiation-associated antigen 5), which promote the transcription of type I interferons (IFN) and … fishing unlimited pier cancer stem cells therapyWebMay 14, 2024 · dna断裂的修复方式你知道吗？ - 大队书记于20240514发布在抖音，已经收获了29个喜欢，来抖音，记录美好生活！ fishing unscrambleWebMar 11, 2024 · Abstract and Figures. IRF1 (Interferon Regulatory Factor-1) is the prototype of the IRF family of DNA binding transcription factors. IRF1 protein expression is … cancers that are mildAnother transcription factor of the IRF family important for antiviral defenses [6, 18], IRF1, has previously also been implicated with the DNA damage response [26]. We hypothesized that upon genotoxic insult, IRF1 might be a downstream target of the RLR/IRF3 pathway, as reported for virus infection [18], and thereby … See more To investigate the molecular links between DNA damage-induced cell death and innate immune signaling, we used A549 human lung carcinoma cells, as they … See more In order to investigate the contribution of antiviral signaling cascades to the induction of DSB-induced cell death, we compared the impact of the major antiviral … See more Above we have shown that RLR/IRF3 signaling as well as expression of IRF1 are important for DNA damage-induced cell death. Furthermore, across all conditions … See more cancer steroids side effectsWebPhospho-IRF7 (Ser437/438) IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to ... fishing uno hook cardWebThe tetramer can exist as a combination of 2 alpha/2 beta, 2 alpha'/2 beta or 1 alpha/1 alpha'/2 beta subunits. Also part of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, which forms following UV irradiation. Interacts with RNPS1. Interacts with SNAI1. fishing uo outlands