WebJan 5, 2024 · Brief Summary: The purpose of this study is to evaluate the efficacy and safety of pemigatinib (INCB054828) in subjects with myeloid/lymphoid neoplasms with … WebINCB54828 (FGFR1/2/3) FIGHT-202; FIGHT-203 Cholangiocarcinoma, bladder cancer. Continued Leadership in MPNs. 15 Goals for next-generation MPN therapies:

INCB054828 (pemigatinib), a potent and selective inhibitor

Web1. 1-2. (canceled) 3. A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: X 1 is CR 1; X 2 is CR 2; X 3 is CR 3; X 4 is N; X 5 is CR 5; X 6 is N; R 1 is H; R 2, R 3, and R 9 are each independently selected from H, halo, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 haloalkyl, C 1-6 haloalkoxy, C 6-10 aryl, C 3-10 cycloalkyl, 5-14 membered … WebThe primary purpose of this research study is to assess how metastatic or surgically unresectable Urothelial Carcinoma with FGF/FGFR alterations responds to treatment with INCB054828. The other goals of the study are to determine how safe and well tolerated the study drug, INCB054828, is, and to obtain data to try and identify patients who would … dvh window sticker

Clinical Trials Register

Web800-548-0828. Get a call from 8005480828? Read comments below to find details about this number. Report unwanted calls to help identify who is calling. WebAbout FGFR and Pemigatinib (INCB54828) Fibroblast growth factor receptors (FGFRs) play an important role in tumor cell proliferation and survival, migration and angiogenesis (the … WebApr 9, 2024 · clinical data from Cohort A of an ongoing Phase 2 trial (Study INCB54828-202) and proposed an indication for accelerated approval of pemigatinib for use in patients … dvs oficina